Abstract: A new material of perissodactyl represented by a crushed skull and the same individual's pair of mandibles (both lost their posterior parts) is described in this paper. The specimen was collected in 1992 by Dr. Wang Yuanqing of IV PP from the late Early Eocene of Danjiangkou, Hubei, China. This new material, Daniiangia pingi gen. et SP. nov., is here referred to Chalicotherioidea and recognized as the earliest known chalicothere. Several relevant issues, such as the early character evolution of chalicothere group, the possible close relationship between chalicothere and palaeothere group and the origin of chalicotheres, will also be tentatively discussed in the present paper.