Abstract: The close relatives of Ctenodactylidae were present early in Eocene of Asia. As basal members of early rodents, they are important for us to understand the early history of rodents. In the present paper a new genus and species, Hohomys lii, referred to Youmyidae, and a specimen of gen. indet., referred to Cocomyidae, are des. cribed. They were collected from Yuhuangding Formation near Wangjiazhai Village, Xijiadian Town, Danjiangkou City (formerly Junxian County), Hubei. The taxa of the vertebrate fauna associated with these two new ctenodactyloid rodents are Rhombomylus cf.turpanensis, R. SP., Advenimus hubeiensis, A. SP., cf. Heptondon sp., Asiocoryphodon conicus, Heterocoryphodon flerowi and Zhongvuanus sichuanensis etc., which suggest an age of late Early Eocene.